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Osteogenic Sarcoma (Osteosarcoma)


Description

Osteogenic sarcoma is the most common type of primary bone cancer and represents two-thirds of the total bone cancer-diagnosed cases. It is mostly a childhood illness; the third most prevalent pediatric cancer which affects the population of 5-25 years old. Osteosarcomas constitute less than 1% of all newly diagnosed tumors in adults, and close to 4% of all newly diagnosed cases in children. It may start at any bone, but it is more likely to happen in the long bones (arms and legs). 

Symptoms

  • Pain and swelling 
  • Bone fractures 
  • Restriction of joint movement 



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Causes

Things that increase your risk to get primary bone cancer include: 

  • History of radiation therapy  
  • Pre-existing bone defects or syndromes such as Paget's Disease 
  • Inherited syndromes caused by genetic impairment 


Diagnostics

  • Imaging tests such as x-rays, bone scans, CT scans, and MRIs. 
  • Blood tests such as the complete blood count. 
  • Bone biopsy to define the tumor grade and help your oncologist to set the proper treatment plan. 



Treatment

There are different treatment options for bone cancer which can be used alone or in combination. The approved treatment plan is decided according to the type, stage, and location of the bone cancer. 

  • Chemotherapy- includes methotrexate, doxorubicin, and cisplatin. 
  • Surgery - includes options ranging from removal of only the cancerous part of the bone to amputation of a limb. 
  • Radiation therapy