Vecovartec 20 mg - 21 F.C. Tablet

-Chronic hypertension: Oral: 20 mg once daily; evaluate response after ~2 to 4 weeks and titrate dose (eg, increase the daily dose by doubling) as needed up to 40 mg once daily; if additional blood pressure control is needed, consider combination therapy. Patients with severe asymptomatic hypertension and no signs of acute end organ damage should be evaluated for medication titration within 1 week. -Non-ST-elevation acute coronary syndrome: Oral: Initial: 20 mg once daily; increase dose as tolerated up to 40 mg/day. -ST-elevation myocardial infarction: Oral: Initial: 20 mg once daily; increase dose as tolerated up to 40 mg/day. -Proteinuric chronic kidney disease: Oral: Initial: 20 mg once daily; can be increased to 40 mg once daily based on blood pressure response and tolerability. Target to an appropriate blood pressure goal and a proteinuria goal of <1 g/day. -Pediatric dosing: -Hypertension: Oral: Children 1 to 5 years and ≥5 kg: Limited data available: Initial: 0.3 mg/kg/dose once daily; if initial response inadequate after 2 weeks, dose may be increased to 0.6 mg/kg/dose once daily. While in case of children and adolescents 6 to 16 years: If the patient weight is 20 to <35 kg: 10 mg once daily; if initial response inadequate after 2 weeks, dose may be increased; maximum daily dose: 20 mg/day, if the patient weight is ≥35 kg: 20 mg once daily; if initial response inadequate after 2 weeks, dose may be increased; maximum daily dose: 40 mg/day. While in case of adolescents >16 years: Initial: 20 mg once daily; if initial response is inadequate, may be increased to 40 mg once daily after 2 weeks.