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Vasotec 80 mg - 14 Scored F.C. Tablet

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Medical Description

Antihypertensive belongs to angiotensin II receptor blockers; used in the treatment of chronic hypertension, acute coronary syndromes, heart failure and proteinuric chronic kidney disease.

Indication & Usage

-Chronic hypertension: For patients who warrant combination therapy (BP >20/10 mm Hg above goal or suboptimal response to initial monotherapy), may use with another appropriate agent (eg, long-acting dihydropyridine calcium channel blocker or thiazide diuretic): Oral: Initial: 80 to 160 mg once daily; evaluate response after ~2 to 4 weeks and titrate dose (eg, increase the daily dose by doubling) as needed up to a maximum of 320 mg once daily; if additional blood pressure control is needed, consider combination therapy. -Acute coronary syndromes: Non–ST-elevation acute coronary syndrome: Oral: Initial: 20 mg twice daily; may increase dose as tolerated up to 160 mg twice daily under close monitoring to avoid hypotension. While in case of ST-elevation myocardial infarction: Oral: Initial: 20 mg twice daily; may increase dose as tolerated up to 160 mg twice daily under close monitoring to avoid hypotension. -Heart failure: Oral: Initial: 20 to 40 mg twice daily; increase dose (eg, double) every ≥2 weeks based on response and tolerability to a target dose of 160 mg twice daily. -Proteinuric chronic kidney disease: Oral: Initial: 40 to 80 mg twice daily depending on BP; can be titrated to 160 mg twice daily based on BP response and tolerability. -Pediatric dosing: -Hypertension: Children and Adolescents <17 years: Oral: Initial: 1 mg/kg/dose once daily; maximum initial daily dose: 40 mg/day; some patients may require a higher initial dose of 2 mg/kg/dose once daily. May titrate to effect up to a maximum daily dose: 4 mg/kg/day not to exceed 160 mg/day. Adolescents ≥17 years: Oral: Initial: 80 mg or 160 mg once daily; some patients may require a higher initial dose. May titrate to effect up to a maximum daily dose: 320 mg/day.

Active Ingredients

Valsartan

Recommended Doctors

No Recommended Doctors Found

Dosage & Administration

-Administer with or without food.

Side Effects

Dizziness, increased blood urea nitrogen, hypotension, orthostatic hypotension, syncope, hyperkalemia, abdominal pain, diarrhea, nausea, upper abdominal pain, neutropenia, viral infection, fatigue, headache, orthostatic dizziness, vertigo, arthralgia, back pain, blurred vision, increased serum creatinine, renal insufficiency and dry cough.

Safety Advice

-Avoid salt substitutes which contain potassium. -Use with caution in case of severe hepatic impairment. -Do not double a dose to make up for a missed dose. -Should not be given to patients suffering from hypersensitivity to valsartan. -Hyperkalemia: May occur; risk factors include renal dysfunction, diabetes mellitus, concomitant use of potassium-sparing diuretics, potassium supplements. -Hypotension: Symptomatic hypotension may occur upon initiation in patients who are salt- or volume-depleted (eg, those treated with high-dose diuretics). -Renal function deterioration: May be associated with deterioration of renal function and/or increases in serum creatinine, particularly in patients with low renal blood flow. -Use with caution in patients with significant aortic/mitral stenosis. -Avoid use in patients with ascites due to cirrhosis or refractory ascites. -Use with caution in patients with unstented unilateral/bilateral renal artery stenosis. -Drugs that act on the renin-angiotensin system can cause injury and death to the developing fetus. Discontinue as soon as possible once pregnancy is detected. -In Black patients, the BP-lowering effects of ARBs may be less pronounced. -Incase of over dose be ready to tell or show what was taken, how much and when it happened, and seek immediate medical attention. For additional information call us on 16676. Always tell your physician your detailed medical history.

Storage

Store at room temperature.

Drug Interactions

-Alfuzosin: May enhance the hypotensive effect of blood pressure lowering agents. -Antipsychotic Agents (Second Generation [Atypical]): blood pressure lowering Agents may enhance the hypotensive effect of Antipsychotic Agents. -Dapoxetine: May enhance the orthostatic hypotensive effect of Angiotensin II Receptor Blockers. -Duloxetine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Duloxetine. -Heparin: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers. -Levodopa-containing products: Blood Pressure Lowering Agents may enhance the hypotensive effect of levodopa-containing products. -Lithium: Angiotensin II Receptor Blockers may increase the serum concentration of Lithium. -Nicorandil: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers. -Nonsteroidal anti-inflammatory agents: Angiotensin II Receptor Blockers may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. -Phosphodiesterase 5 Inhibitors: May enhance the hypotensive effect of blood pressure lowering agents. -Potassium Salts: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers. -Potassium-Sparing Diuretics: Angiotensin II Receptor Blockers may enhance the hyperkalemic effect of Potassium-Sparing Diuretics. -trimethoprim: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers.

Pregnancy & Lactation

-Drugs that act on the renin-angiotensin system can cause injury and death to the developing fetus. -It is not known if valsartan is present in breast milk. Due to the potential for serious adverse reactions in the breastfed infant, breastfeeding is not recommended while using valsartan. -Ask your physician before taking any medication during pregnancy or lactation.

Manufacture

EIPICO

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