Napifit 100 Mg - 8 F.C. Tablet

-Erectile dysfunction: Oral: 50 mg once daily as needed 1 hour before sexual activity; may be taken up to 4 hours before sexual activity. Reduce to 25 mg once daily if side effects occur. May increase to a maximum dose of 100 mg once daily if there is incomplete response. -Pulmonary arterial hypertension: Oral: 20 mg 3 times daily; some experts do not recommend titration to higher doses. However, in patients who fail to demonstrate or maintain an adequate clinical response, other experts consider slowly increasing the dose in 20 mg increments to a maximum dose of 80 mg 3 times daily. IV: 10 mg 3 times daily. -Raynaud disease: Oral: Initial: 20 mg once or twice daily; based on response and tolerability, may increase to 20 mg 3 times daily as needed; if lower doses are ineffective, may increase further to 40 mg 3 times daily if tolerated. -Pediatric dosing: pulmonary hypertension: Limited data available: Oral: Infants: Initial: 0.25 mg/kg/dose every 6 hours or 0.5 mg/kg/dose every 8 hours; titrate as needed; maximum reported dose range: 1 to 2 mg/kg/dose every 6 to 8 hours. Children and Adolescents <18 years of age: Note: Dosage should not be increased; higher doses and long-term use are associated with an increased mortality risk, 8 to 20 kg: 10 mg three times daily, >20 kg to 45 kg: 20 mg three times daily, >45 kg: 40 mg three times daily.