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Choletimb 10 mg - 14 Tablet

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Medical Description

Antilipidemic agent used in the treatment of hypercholesterolemia and in the secondary prevention of atherosclerotic cardiovascular diseases.

Indication & Usage

-Homozygous familial hypercholesterolemia: Oral: 10 mg once daily. -Secondary prevention of atherosclerotic cardiovascular events after acute coronary syndrome: Oral: 10 mg once daily.

Active Ingredients

Ezetimibe

Recommended Doctors

No Recommended Doctors Found

Dosage & Administration

-Administered without regard to meals. -Should be administered ≥2 hours before or ≥4 hours after bile acid sequestrants.

Side Effects

-Increased serum transaminases and hepatotoxicity, myalgia, myopathy and rhabdomyolysis. -Arthralgia, sinusitis, upper respiratory tract infection and increase in gamma-glutamyl transferase.

Safety Advice

-Should not be given to patients suffering from hypersensitivity to ezetimibe. -Should not be given to patients with active hepatic disease or unexplained persistent elevations in serum transaminases. -Use with caution in patients with severe renal impairment. -In case of over dose be ready to tell or show what was taken, how much and when it happened, and seek immediate medical attention. For additional information call us on 16676. Always tell your physician your detailed medical history.

Storage

Store at room temperature.

Drug Interactions

-Bile Acid Sequestrants: May decrease the absorption of Ezetimibe. -Cyclosporine (Systemic): Ezetimibe may increase the serum concentration of Cyclosporine. -Fenofibrate and Derivatives: May enhance the adverse/toxic effect of Ezetimibe.

Pregnancy & Lactation

-Use is contraindicated in pregnant women who require combination therapy with an HMG-CoA reductase inhibitor. If treatment for familial hypercholesterolemia is needed during pregnancy, other agents are preferred. -It is not known if ezetimibe is present in breast milk, the decision to continue or discontinue breastfeeding during therapy should consider the risk of exposure to the infant and the benefits of treatment to the mother. Use is contraindicated in breastfeeding women who require combination therapy with an HMG-CoA reductase inhibitor. -Ask your physician before using any medication during pregnancy or lactation.

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