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Augmentin 62.5 mg/ ML Infant Drops 20 ML

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هذه الصفحة قد لا تغطي جميع المعلومات المذكورة في نشرة الشركة المصنعة المرفقة

الوصف الطبي

Antibiotic, belongs to the penicillin group used in the treatment of bacterial rhinosinusitis, pneumonia, otitis media, prophylaxis or treatment against bite wound infection, diabetic foot infection, odontogenic infection and urinary tract infection.

الدلالة و الاستخدام

-Pediatric dosing: Warning: The doses below are based on the amoxicillin component only. -Frequency of dosing generally based on ratio of amoxicillin to clavulanate: 2:1 formulations are dosed 3 times daily (amoxicillin 250 mg/clavulanate 125 mg), 4:1 formulations are dosed 3 times daily (amoxicillin 125 mg/clavulanate 31.25 mg; amoxicillin 250 mg/clavulanate 62.5 mg; amoxicillin 500 mg/clavulanate 125 mg), 7:1 formulations are dosed 2 times daily (amoxicillin 200 mg/clavulanate 28.5 mg; amoxicillin 400 mg/clavulanate 57 mg; amoxicillin 875 mg/clavulanate 125 mg) and 14:1 formulations are dosed 2 times daily (amoxicillin 600 mg/clavulanate 42.9 mg). -General dosing for the susceptible infections: Immediate-release formulations: Infants, children and adolescents: Oral: 4:1 formulation: 20 to 40 mg amoxicillin/kg/day in divided doses 3 times daily; maximum daily dose: 1,500 mg/day, 7:1 formulation: 25 to 45 mg amoxicillin/kg/day in divided doses twice daily; maximum daily dose: 1,750 mg/day, 14:1 formulation: 90 mg amoxicillin/kg/day in divided doses twice daily; maximum daily dose: 4,000 mg/day. -Acute otitis media: Infants ≥3 months and children: Oral suspension (600 mg/5 mL): Oral: 90 mg amoxicillin/kg/day divided every 12 hours for up to 10 days. -Pneumonia: Infants ≥3 months, children, and adolescents: Empiric therapy: Oral: 90 mg amoxicillin/kg/day in divided doses twice daily; maximum daily dose: 4,000 mg/day. -For the rest of pediatric dosing see dosage and administration.

المكونات النشطة

Clavulanic AcidAmoxicillin

دكاترة مرشحين

لم يتم العثور على دكاترة مرشحين

الجرعة و طريقة الاستعمال

-Administer around-the-clock. -Administer with food to increase absorption and decrease stomach upset. -Suspension: shake suspension well before use. -Pediatric dosing (continue): -Acute bacterial rhinosinusitis: Infants ≥3 months: Oral: 45 mg amoxicillin/kg/day divided every 12 hours. While in case of children and adolescents: Oral: Standard dose: 45 mg amoxicillin/kg/day divided every 12 hours for 10 to 14 days, High dose: 80 to 90 mg amoxicillin/kg/day divided every 12 hours; maximum dose: 2,000 mg/dose. -IV dosing: 5:1 formulation: Infants <3 months or weighing <4 kg: IV: 25 mg amoxicillin/kg/dose every 12 hours, infants ≥3 months weighing ≥4 kg, children, and adolescents: IV: 25 mg amoxicillin/kg/dose every 8 hours; maximum dose: 1,000 mg amoxicillin/dose. Or 10:1 formulation: Infants <3 months or weighing <4 kg: IV: 50 mg amoxicillin/kg/dose every 12 hours, while in case of infants ≥3 months, children, and adolescents weighing 4 to <40 kg: 50 mg amoxicillin/kg/dose every 8 hours; maximum dose: 2,000 mg amoxicillin/dose, while in case of children and adolescents weighing ≥40 kg: 2,000 mg amoxicillin every 8 to 12 hours.

الاّثار الجانبية

-Antibiotic-associated diarrhea (AAD), nausea, and vomiting, Clostridioides difficile infection (CDI), drug-induced liver injury, urticaria, angioedema and anaphylaxis. -Diaper rash, skin rash, urticaria, nausea, vomiting, vaginitis, candidiasis, vaginal mycosis, abdominal distress, flatulence, thrombocythemia and headache.

نصائح احترازية

-Should not be given to patients suffering from hypersensitivity to amoxicillin, clavulanic acid, other beta-lactam antibacterial drugs. -Use is contraindicated in patients with a history of amoxicillin and clavulanate-associated hepatic dysfunction. -In case of renal impairment: If the creatinine clearance is 10 to <30 mL/minute: 250 to 500 mg every 12 hours, If the creatinine clearance is <10 mL/minute: 250 to 500 mg every 12 to 24 hours. -Prolonged use may result in fungal or bacterial superinfection. -In case of over dose be ready to tell or show what was taken, how much and when it happened, and seek immediate medical attention. For additional information call us on 16676. Always tell your physician your detailed medical history.

التخزين

Store at room temperature.

تفاعلات الأدوية

-Allopurinol: May enhance the potential for allergic or hypersensitivity reactions to Amoxicillin. -Aminoglycosides: Penicillins may decrease the serum concentration of Aminoglycosides. -Acemetacin: May increase the serum concentration of Penicillins. -BCG Vaccine (Immunization): Antibiotics may diminish the therapeutic effect of BCG Vaccine. -Methotrexate: Penicillins may increase the serum concentration of Methotrexate. -Mycophenolate: Penicillins may decrease serum concentrations of the active metabolite(s) of Mycophenolate. -Sodium Picosulfate: Antibiotics may diminish the therapeutic effect of Sodium Picosulfate. -Tetracyclines: May diminish the therapeutic effect of Penicillins. -Vitamin K Antagonists (eg, warfarin): Penicillins may enhance the anticoagulant effect of Vitamin K Antagonists.

الحمل والرضاعة

-Both amoxicillin and clavulanic acid cross the placenta. An increased risk of necrotizing enterocolitis in neonates or bowel disorders in children may be associated with amoxicillin/clavulanate when exposure occurs near delivery, as a class, penicillin antibiotics are widely used in pregnant women. Based on available data, penicillin antibiotics are generally considered compatible for use during pregnancy, Amoxicillin/clavulanate is considered compatible for the of treatment airway diseases in pregnant women. Use should be avoided in women at risk for preterm delivery. -Amoxicillin is present in breast milk following administration amoxicillin/clavulanate. The relative infant dose (RID) of amoxicillin following administration of amoxicillin/clavulanate is 0.02% to 0.07%. In general, breastfeeding is considered acceptable when the RID is <10%, amoxicillin/clavulanate is considered compatible with breastfeeding when used in usual recommended doses. -Ask your physician before taking any medication during pregnancy or lactation.

صناعة

GLAXO SMITHKLINE

ملاحظة

أظهر المزيد

عنوان التوصيل

إضافة عنوان

هل تريد مسح العنوان المسجل ؟

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