Medical Description
Nonsteroidal Anti-inflammatory Drug used in the treatment of acute coronary syndrome, primary and secondary prevention of atherosclerotic cardiovascular diseases, prevention of preeclampsia and used in the prophylaxis against venous thromboembolism.
Indication & Usage
- Prevention of arterial thromboses after surgeries involving the coronary vessels
- Prevention of strokes after preliminary stages have occurred.
-Prevention of arterial thromboses (bloodclots in coronary vessels) and after a myocardial infarction (reinfarction prophylaxis.
-Treatment of unstable angina pectoris.
-Treatment of an acute myocardial infarction.
-Prevention of arterial thromboses after surgeries on blood vessels
Active Ingredients
Acetylsalicylic Acid
Dosage & Administration
-Prevention of arterial thromboses without bypass surgery on the coronary vessels and
after dilation (balloon dilation) of constricted coronary vessels: 100 mg/day.
-Prevention of arterial thromboses after bypass surgery on the coronary vessels and
after dilation (balloon dilation) of constricted coronary vessels: 100–300 mg/day.
-Prevention of strokes: 3 × 100 mg/day.
-Prevention of thromboses after myocardial infarction and treatment of unstable angina
pectoris: 1 × 100 mg/day.
-Prevention of heart attacks in patients after a high risk was determined by a physician:
1 × 100 mg/day
Side Effects
Stomach problems are a common side effect. Asthma, digestive problems, nausea, vomiting
and diarrhoea were reported occasionally. Hypersensitivity reactions (such as swelling of
the skin and mucous membranes (e.g. stuffy nose), skin rashes, shortness of breath, drop in blood pressure up to shock) as well as gastrointestinal bleeding and gastrointestinal ulcers, which very rarely may lead to perforations may occur in rare cases. Headaches, dizziness, tinnitus, visual impairment, hearing impairment, states of confusion, anaemia due to iron deficiency as well as renal and hepatic dysfunctions rarely occur.
Safety Advice
-Allergy Not recommended for patients with known allergy to aspirin or those with bleeding disorders
-Not recommended for patients with the history of peptic ulcer disease.
-aspirin protect is not recommended for children and adolescents under the age of 18.
-Taking Aspirin Protect and antidiabetic drugs (e.g. insulin, sulphonylureas) at the same time may lower the blood sugar level.
-Not recommended in children with varicella infections or influenza-like illnesses due to the risk of Reye's syndrome.
-Asthma - It is not recommended in patients with the known history of it-sensitive asthma.
-Incase of over dose be ready to tell or show what was taken, how much and when it happened, and seek immediate medical attention. For additional information call us on 16676. Always tell your physician your detailed medical history
Storage
Store at room temperature
Drug Interactions
-Agents with Antiplatelet Properties (e.g., P2Y12 inhibitors, NSAIDs, SSRIs, etc.): May enhance the adverse/toxic effect of Salicylates. Increased risk of bleeding may result.
-Agents with Blood Glucose Lowering Effects: Salicylates may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects.
-Alcohol (Ethyl): May enhance the adverse/toxic effect of Aspirin. Specifically, alcohol may increase the bleeding risk of aspirin. Alcohol (Ethyl) may diminish the therapeutic effect of Aspirin. Specifically, alcohol may interfere with the controlled release mechanism of extended release aspirin.
-Alendronate: Aspirin may enhance the adverse/toxic effect of Alendronate. Specifically, the incidence of upper gastrointestinal adverse events may be increased
-Angiotensin-Converting Enzyme Inhibitors: Salicylates may enhance the nephrotoxic effect of Angiotensin-Converting Enzyme Inhibitors. Salicylates may diminish the therapeutic effect of Angiotensin-Converting Enzyme Inhibitors.
-Calcium Channel Blockers (Nondihydropyridine): May enhance the antiplatelet effect of Aspirin
-Corticosteroids (Systemic): Salicylates may enhance the adverse/toxic effect of Corticosteroids (Systemic). These specifically include gastrointestinal ulceration and bleeding. Corticosteroids (Systemic) may decrease the serum concentration of Salicylates. Withdrawal of corticosteroids may result in salicylate toxicity.
-Ginkgo Biloba: May enhance the anticoagulant effect of Salicylates. Management: Consider alternatives to this combination of agents.
Pregnancy & Lactation
-Low-dose aspirin is recommended to prevent preeclampsia in patients at high risk (history of preeclampsia, multifetal gestation, chronic hypertension, type 1 or type 2 diabetes mellitus, renal disease, autoimmune disease [systemic lupus erythematosus, antiphospholipid syndrome])
-low dose aspirin (≤150 mg/day) is not associated with the same risks as higher doses and has a positive effect on some pregnancy outcomes
-High doses of aspirin while breastfeeding are not recommended due to the theoretical risk of Reye syndrome
Manufacture
BAYER HEALTHCARE