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Aprovel 150 mg - 14 Tablet

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هذه الصفحة قد لا تغطي جميع المعلومات المذكورة في نشرة الشركة المصنعة المرفقة

الوصف الطبي

Angiotensin II receptor blocker used in the treatment of chronic hypertension, acute coronary syndromes and proteinuric chronic kidney diseases.

الدلالة و الاستخدام

-Chronic hypertension: Oral: 150 mg once daily; evaluate response after ~2 to 4 weeks and titrate dose (eg, increase the daily dose by doubling) as needed up to 300 mg once daily; if additional blood pressure control is needed, consider combination therapy. Patients with severe asymptomatic hypertension and no signs of acute end organ damage should be evaluated for medication titration within 1 week. -Acute coronary syndromes: In case of non–ST-elevation acute coronary syndrome: Oral: Initial: 150 mg once daily; increase dose as needed based on response and tolerability up to a maximum dose of 300 mg once daily. While in case of ST-elevation myocardial infarction: Oral: Initial: 150 mg once daily; increase dose as needed based on response and tolerability up to a maximum dose of 300 mg once daily. -Proteinuric chronic kidney disease: Oral: Initial: 150 mg once daily; titrate as needed based on BP response and tolerability up to a maximum dose of 300 mg once daily. Target to an appropriate BP goal and a proteinuria goal of <1 g/day. -Pediatric dosing: -Hypertension: Limited data available: Children ≥6 years: Oral: Initial: 75 mg once daily; may be titrated to a maximum dose of 150 mg once daily. While in case of adolescents: Oral: Initial: 150 mg once daily; may be titrated to a maximum dose of 300 mg once daily.

المكونات النشطة

Irbesartan

دكاترة مرشحين

لم يتم العثور على دكاترة مرشحين

الجرعة و طريقة الاستعمال

Administer with or without food.

الاّثار الجانبية

Hyperkalemia, orthostatic hypotension, diarrhea, dyspepsia, heartburn, dizziness, fatigue, orthostatic dizziness, urticaria, anemia, thrombocytopenia, hepatitis, increased liver enzymes, jaundice, anaphylactic shock, anaphylaxis, angioedema, increased phosphokinase in blood specimen and tinnitus.

نصائح احترازية

-Should not be given to patients suffering from hypersensitivity to irbesartan. -May cause hyperkalemia. -Use a lower starting dose of 50% of the recommended initial dose in volume- and salt-depleted patients. -Symptomatic hypotension may occur upon initiation of therapy in patients who are salt- or volume-depleted. -May be associated with deterioration of renal function and/or increases in serum creatinine, particularly in patients with low renal blood flow. -Use with caution in patients with significant aortic/mitral stenosis. -Avoid use in patients with ascites due to cirrhosis. -Use with caution in patients with unstented unilateral/bilateral renal artery stenosis. -The BP-lowering effects of ARBs may be less pronounced in black patients. -In case of over dose be ready to tell or show what was taken, how much and when it happened, and seek immediate medical attention. For additional information call us on 16676. Always tell your physician your detailed medical history.

التخزين

Store at room temperature.

تفاعلات الأدوية

-Alfuzosin: May enhance the hypotensive effect of blood pressure lowering agents. -Antipsychotic Agents: blood pressure lowering agents may enhance the hypotensive effect of Antipsychotic Agents. -Dapoxetine: May enhance the orthostatic hypotensive effect of Angiotensin II Receptor Blockers. -Duloxetine: blood pressure lowering agents may enhance the hypotensive effect of Duloxetine. -Heparin: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers. -Levodopa-containing products: blood pressure lowering agents may enhance the hypotensive effect of Levodopa-containing products. -Lithium: Angiotensin II Receptor Blockers may increase the serum concentration of Lithium. -Nicorandil: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers. -Nonsteroidal Anti-Inflammatory Agents: Angiotensin II Receptor Blockers may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents. -Phosphodiesterase 5 Inhibitors: May enhance the hypotensive effect of blood pressure lowering agents. -Potassium Salts: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers. -Potassium-Sparing Diuretics: Angiotensin II Receptor Blockers may enhance the hyperkalemic effect of Potassium-Sparing Diuretics. -Trimethoprim: May enhance the hyperkalemic effect of Angiotensin II Receptor Blockers.

الحمل والرضاعة

-Drugs that act on the renin-angiotensin system can cause injury to the developing fetus. -It is not known if Irbesartan is present in breast milk. Due to the potential for serious adverse reactions in the breastfeeding infant, breastfeeding is not recommended during the treatment. -Ask your physician before taking any medication during pregnancy or lactation.

صناعة

SANOFI

ملاحظة

أظهر المزيد

عنوان التوصيل

إضافة عنوان

هل تريد مسح العنوان المسجل ؟

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